Understanding mechanisms and effects of inflammation can inform a range of medical questions in allergy management, autoimmunity, intra- and extracellular pathology, cell-mediated and humoral immune responses.
The inflammation cluster of LUNARIS™ Kits targets meaningful selections of secreted and soluble cytokines implicated in T cell differentiation and effector functions. Unlike other comparable cytokine quantification methods, the kits allow measuring protein concentrations from single-digit pg/mL levels to 3–4 log scales higher in low-volume clinical samples.
Research over the last few decades has uncovered a growing number of biomarkers of eye diseases and dysfunctions that have proven indispensable as diagnostic and therapeutic indicators.
The ophthalmology cluster of LUNARIS™ Kits constitutes a trailblazing solution for examining cytokines, angiogenesis markers, and chemokines associated with eye pathologies because they enable their detection in rare, low-volume and even viscous ocular samples from human clinical interventions or mouse models.
Cytokine profiles offer a telltale snapshot of immune function that can inform treatment decisions in next-generation cancer therapies. Progress in stem cell therapy can be monitored, adding valuable information for decisions about next treatment steps. Sensitive detection of cytokines can reveal susceptibility of cancer tumors to immune-based strategies like adoptive T cell-mediated immunotherapy, or to antibody-based cancer drugs.
The immuno-oncology cluster of LUNARIS™ Kits enables sensitive detection of multiple relevant cytokines in a single, small, minimally invasive biofluid sample.